By working at the interface between engineering and biology, we investigate the spatial and temporal effects of various micro-environmental factors, including three-dimensionality of the cell environment and isotropy of the applied forces, on stem cell renewal and differentiation.
Our skills in 3D:
We develop frontier tools for cell modelling, including microengineered stem cell niches, microfluidic bioreactors and miniaturised windows for intravital imaging. Our long-term goal is to develop the potential of engineered tissue-equivalents and organoids in in biological research applied to cell modelling, drug discovery and regenerative medicine.
Fundede research projects: