Organic Synthesis, Catalysis, and Materials Laboratory

• subjectSkills

  The O^SCM Lab (Organic @ Synthesis, Materials and Catalysis)stems from the convergence of different but complementary skill sets in the field of organic synthesis and physical organic chemistry:

   

  • Total synthesis and complete characterization of
    • organic molecules, also by developing multicomponent approaches;
    • organic molecules by microwave assisted chemistry
    • supramolecular micro- and nano-structures, including a) Metal-Organic Frameworks (MOFs), Nanocages, and Poly-[n]-catenanes, b) hydro-, organo-, and xero-gels, c) biomass-based materials;
    • peptidomimetics and gene/drug delivery vectors;
    • peptides (by automated solid-phase system);
    • homogeneous and heterogeneous (organo-)catalysts for (aerobic) oxidations and other chemical transformations

   

  • Single crystal X-ray diffraction analysis;
  • ab initio powder XRD structure solution;
  • high temperature solid-sate chemistry;
  • single-crystal-to-single-crystal transformations

• subjectResearch activities

  Design and synthesis of: i) receptor and/or sensor molecules for the recognition of ions in solution; ii) coordination polymers for the selective adsorption of volatile organic compounds; iii) supramolecular hydro-, organo- and xerogels for sensing of volatile compounds;

  Design and synthesis hybrid metal organic materials by fast and slow crystallization methods. Ab initio powder XRD techniques for determination of their crystal structure and studies on their solid-state and mechanochemical reactivity.

  Synthesis of small molecules/peptidomimetics/peptides as antimicrobial agents. Design of (fluorinated) cationic lipids and polymers as gene and drug delivery vectors

  Multicomponent approach for the synthesis of heterocyclic compounds. Design and synthesis of ligands for metal catalysis. 

  Synthesis of hydrogels and nanogels for biomedical applications.

  Eco-design of micro-/nano-structured organic materials from biomass for i) water, air, and soil remediation, ii) sensing, iii) building materials, iv) catalysis, v) (phyto)drugs delivery.

  Development of catalytic systems for selective oxidation of organic substrates.

• peoplePhD

  ALESSIO MARIA CARAMIELLO

  CAROLA ROMANI

• linkKeywords

  Biochemicals

  Biomaterials

  Biomedicine

  Biomimetic

  Catalysis

  Chiral Drugs

  Crystal Engineering

  Crystallography

  Drug Delivery

  Fluorinated drugs

  Fluorinated Materials

  Gene Delivery

  Green Chemistry

  Halogen bond

  Heterocyclic Compounds

  Homogeneous Catalysis

  Host-Guest Chemistry

  Hydrogen bonding

  Materials Functionalization

  Medicinal Chemistry

  Molecular dynamics simulations

  Molecular Transporters

  Multi-component Reactions

  Nanocellulose

  Nanomaterials

  Nanomedicine

  NMR

  Organic Chemistry

  Organic Synthesis

  Peptidomimetics

  Pollutant Reduction

  Polymer Crystallization and Morphology

  Polymers

  Radicals

  Renewable Sources

  Responsive Materials

  Smart Materials

  Soft Matter

  Solid State Chemistry

  Structure-property Relationship

  Supramolecular Chemistry

  Sustainable Chemistry

  Sustainable Processes

  X-Ray diffraction