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Claudia Pigliacelli is an Associate Professor in the Department of Chemistry, Materials and Chemical Engineering “Giulio Natta” at Politecnico di Milano. She obtained her PhD in Pharmaceutical Sciences from the University of East Anglia (United Kingdom) in 2015.

She carried out research activities as a research fellow at Politecnico di Milano (2013–2016) and subsequently as a postdoctoral researcher at Aalto University (Finland, 2016–2019) and at the Centro de Investigacións Científicas Avanzadas (CICA), Universidade da Coruña (Spain, 2020).

Her current research focuses on:

• nanostructured peptide- and protein-based systems for biomedical applications;
• synthesis and self-assembly of gold nanoparticles and nanoclusters and their use in sensing applications;
• drug delivery using polymeric and peptide-based systems.

Selected Publications

• Tailoring Nanocellulose with Short Amyloidogenic Peptides for Improved Mechanical Strength and Barrier Performance, A. Marchetti et al., J. Mater. Chem. B 2024, 12, 9229.
• Interaction of polymers with bile salts – Impact on solubilisation and absorption of poorly water-soluble drugs, C. Pigliacelli et al., Colloids and Surfaces B: Biointerfaces 2023, 222, 113044.
• High-Resolution Crystal Structure of a 20 kDa Superfluorinated Gold Nanocluster, C. Pigliacelli et al., Nature Communications 2022 13 (1), 1-8.
• Probing the molecular interactions between pharmaceutical polymeric carriers and bile salts in simulated gastrointestinal fluids using NMR spectroscopy, C. Pigliacelli et al., Journal of Colloids and Interface Science 2019, 551, 1, 147-154.
• In Situ Generation of Chiroptically-Active Peptide-Gold Superstructures Promoted by Iodination, C. Pigliacelli et al., ACS Nano 2019, 13, 2, 2158-2166.
• Encapsulation of Fluorinated Drugs in the Confined Space of Water-Dispersible Fluorous Gold Supraparticles, C. Pigliacelli et al., Angewandte Chemie International Edition, 2017, 56, 16186-16190.

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